Alan Faden

Alan Faden, MD

Professor and Center Director, Department of Anesthesiology

SCHOOL OF MEDICINE

  • Research interests

    TBI

    SCI

    Mechanisms of chronic pain and its modulation after spinal cord injury

  • Research approaches

    modeling

    behavior

    molecular/cellular biology

    pharmacology






    ORCID ID: orcid.org/0000-0003-0128-2348

Publications

  1. Wu J, Renn CL, FADEN AI, Dorsey SG. TrkB.T1 contributes to neuropathic pain following spinal cord injury through regulation of cell cycle pathways. Journal of Neuroscience, 24 July 2013, 33(30):12447-12463; doi:10.1523/JNEUROSCI.0846-13.2013

  2. Wu J, Zhao Z, Sabirzhanov B, Stoica BA, Kumar A, Luo T, Skovira J, FADEN AI. Spinal cord injury causes brain inflammation associated with cognitive and affective changes: role of cell cycle pathways. J Neurosci, 34(33):10989-11006, 2014.

  3. Lipinski, M. M., Liu, S., Sarkar, C., Dinizo, M., FADEN AI, Koh, E., & Wu, J. (2014). Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death. Cell Death and Disease 2014 Nov 11:0. [Epub ahead of print].

  4. Wu J, Zhao Z, Zhu X, Renn CL, Dorsey SG, FADEN AI. Cell cycle inhibition limits development and maintenance of neuropathic pain following spinal cord injury. Pain. 2016 Feb;157(2):488-503. doi: 10.1097/j.pain.0000000000000393.PMID: 26797506.

  5. Matyas JJ, O'Driscoll CM, Yu L, Coll-Miro M, Daugherty S, Renn CL, FADEN AI, DorseySG, Wu J.Truncated TrkB.T1-mediated astrocyte dysfunction contributes to impaired motor function and neuropathic pain after spinal cord injury. J Neurosci. 2017 Mar 7. pii: 3353-16.[Epub ahead of print] PMID: 28270575.