CACPR is affiliated with the University of Maryland, Baltimore
The University of Maryland Center to Advance Chronic Pain Research

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Andrew Coop, PhD

Andrew-Coop

Andrew Coop, PhD

Professor and Associate Dean for Academic Affairs, Pharmaceutical Sciences

SCHOOL OF PHARMACY

Research interests

New analgesics lacking the undesired effects of opioids

Research approaches

Synthetic chemistry

Lab or individual page: http://faculty.rx.umaryland.edu/acoop/

Publications

T. B. Haddou, D. Malfacini, G. Calo, M. D. Aceto, L. S. Harris, J. R. Traynor, A. Coop, H. Schmidhammer, M. Spetea. Exploring pharmacological activities and signaling of morphinans substituted in position 6 as potent agonists interacting with the μ opioid receptor. Molecular Pain 2014, 10, 48.

M. D. Metcalf, A. D. Rosicky, H. E. Hassan, N. D. Eddington, A. Coop, C. W. Cunningham, S. L. Mercer. Opioids and efflux transporters. Part 4: Influence of N-substitution on P-glycoprotein substrate activity of noroxymorphone analogues. Bioorg. Med. Chem. Lett., 2014, 24, 3592-3595.

J. R. Healy, P. Bezawada, J. Shim, J. W. Jones, M. A. Kane, A. D. MacKerell, Jr, A. Coop, R. R. Matsumoto. Synthesis, Modeling, and Pharmacological Evaluation of UMB 425, a Mixed μ Agonist/δ Antagonist Opioid Analgesic with Reduced Tolerance Liabilities. ACS Chemical Neuroscience 2013, 4, 1256-1266.

Also see: http://www.baltimoresun.com/health/bs-hs-new-opioid-20160624-story.html
and http://www.theatlantic.com/magazine/archive/2016/06/the-future-of-getting-high/480735/

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