Simon Akerman, PhD
Simon Akerman, Ph.D.
Associate Professor, Department of Neural and Pain Sciences
SCHOOL OF DENTISTRY
Research interests
Pathophysiology of primary headaches inc.
Migraine
Cluster Headache
Animal models of primary headaches
TMDs
Research approaches
Physiological methods in rodents
In vivo Electrophysiology
Laser Doppler Flowmetry
Video Imaging
Pain behaviors
Publications
1. S Akerman, B Simon and M Romero-Reyes (2017) Vagus nerve stimulation suppresses acute noxious activation of trigeminocervical neurons in animal models of primary headache. Neurobiol Dis. 102:96-104.
2. AP Andreou, PR Holland, S Akerman, O Summ, J Frederik, PJ Goadsby (2016) Transcranial Magnetic Stimulation and Potential Cortical and Trigeminothalamic Mechanisms in Migraine. Brain. 139:2002-2014.
3. S Akerman and PJ Goadsby (2015) Neuronal PAC1 receptors mediate delayed activation and sensitization of trigeminocervical neurons: Relevance to migraine. Sci Trans Med. 7:308ra157.
4. M Romero-Reyes, V Pardi and S Akerman (2015) A potent and selective calcitonin gene-related peptide (CGRP) receptor antagonist, MK-8825, inhibits responses to nociceptive trigeminal activation: role of CGRP in orofacial pain. Exp Neurol. 271:95-103.
5. S Akerman, PR Holland, MP Lasalandra and PJ Goadsby (2013) Endocannabinoids in the brainstem modulate dural trigeminovascular nociceptive traffic via CB1 and 'triptan' receptors: implications in migraine. J Neurosci. 33:14869-14877.