Susan G. Dorsey, PhD, RN, FAAN

Research interests

Brain-derived neurotrophic factor (BDNF) signaling and chronic pain plasticity

Role of the dorsal horn in chronic pain plasticity following spinal cord injury (SCI)

Genomics of pain

Chemotherapy-induced peripheral neuropathy

Development and behavioral phenotyping of clinically relevant rodent models of acute and chronic pain
Research approaches

Extracellular recording in vivo; microarray platforms for analysis of RNA expression, DNA methylation, miRNA expression and genotyping; next-generation sequencing of RNA and DNA; rodent behavioral phenotyping; bioinformatics; molecular biology; cell culture; QST; immunohistochemistry and immunocytochemistry

ORCID: 0000-0001-7648-1312

Publications

Traub RJ, Cao D-Y, Karpowicz J, Pandya S, Ji Y, DORSEY SG and Dessem D (2014). A clinically relevant animal model of temporomandibular disorder and irritable bowel syndrome comorbidity. J Pain, 15, 956-966. PMID: 24981128
Wu J, Renn CL, Faden AI and DORSEY SG (2013). TrkB.T1 contributes to neuropathic pain following spinal cord injury through regulation of cell cycle pathways. J Neurosci, 33, 12447-12463. PMID: 23884949
Griffith K, Couture DJ, Zhu S, Pandya N, Johantgen ME, Cavaletti G, Davenport JM, Tanguay LJ, Choflet A, Milliron T, Glass E, Gambill N, Renn CL and DORSEY SG (2013). Evaluation of chemotherapy-induced peripheral neuropathy using current perception threshold and clinical evaluations. Supportive Care in Cancer, 22, 1161-1169. PMID: 24362842
Renn CL, Carozzi VA, Rhee P, Gallop D, DORSEY SG and Cavaletti G (2011). Multimodal assessment of painful peripheral neuropathy induced by chronic oxaliplatin-based chemotherapy in mice. Molecular Pain Apr 26; 7:29. PMID: 21521528
Quartu M, Carozzi V, DORSEY SG, Serra MP, Poddighe L, Picci C, Boi M, Del Fiacco M, Chiorazzi A, Renn CL, Cavaletti G and Marmiroli P (2014). Bortezomib treatment produces nocifensive behavior and changes in the expression of TRPV1, CGRP and Substance P in the rat DRG, spinal cord and sciatic nerve. Biomed Research International: Toxicology, 180428. PMID: 24877063