Ying He, PhD
Ying He, PhD
Assistant Professor, Department of Pharmaceutical Sciences
SCHOOL OF PHARMACY
Research interests
Molecular pharmacology of chronic pain
Pain in sickle cell disease, cancer
Mechanisms of opioid addiction
Research approaches
Pharmacology
molecular biology
behavioral neuroscience
Publications
He Y, Wilkie DJ, Nazari J, Wang R, Messing RO, DeSimone J, Molokie RJ, Wang ZJ. (2016). PKCd-targeted intervention relieves chronic pain in a murine sickle cell disease model. J Clin Invest;126(8):3053-7. PMID: 27348590
He Y, Wang ZJ. (2015) Nociceptor beta II, delta, and epsilon isoforms of PKC differentially mediate paclitaxel-induced spontaneous and evoked pain. J Neurosci; 35(11):4614-25. PMID: 25788678
He Y, Chen Y, Tian X, Yang C, Lu J, Xiao C, DeSimone J, Wilkie DJ, Molokie RE, Wang ZJ. (2016) CaMKIIα underlies spontaneous and evoked pain behaviors in Berkeley sickle cell transgenic mice. Pain; 157(12):2798-2806. PMID: 27842048
Corder G, Doolen S, Donahue RR, Winter MK, Jutras BL, He Y, Hu X, Wieskopf JS, Mogil JS, Storm DR, Wang ZJ, McCarson KE, Taylor BK. (2013) Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence. Science; 341(6152):1394-9. PMID: 24052307
He Y, Tian X, Hu X, Porreca F, Wang Z. (2012) Negative reinforcement reveals non-evoked ongoing pain in mice with tissue or nerve injury. J Pain; 13(6):598-607. PMID: 22609247